The involvement of developing countries in international clinical trials is necessary for the development of appropriate medicines for local populations. However, the absence of appropriate structures for ethical review represents a barrier for certain countries. Currently there is very little information available on existing structures dedicated to ethics in western and central Africa. This article briefly describes historical milestones in the development of networks dedicated to capacity building in ethical review in these regions and outlines the major conclusions of two (...) workshops on this issue, which were held in September and October 2002 in Libreville, Gabon, and Paris, France. The workshops were the culmination of collaboration between the African Malaria Network Trust (AMANET) and the Pan African Bioethics Initiative (PABIN). They produced an update on ethics organizations with regard to mission, function, activities, members, and contact people, in eight countries within the regions discussed. As a result of the commitment of mandated delegates, a further prominent outcome followed these workshops: the creation of national structures, where none existed before, dedicated to the ethical review of clinical trials. (shrink)

In the first English translation of his work, Laruelle explores the major European thinkers from Nietzsche to Derrida to define his own 'non-philosophical' ...

Philosophical discussions on the ways that death makes life meaningful and sacred.

In this highly insightful analysis of Western and Chinese concepts of efficacy, François Jullien subtly delves into the metaphysical preconceptions of the two civilizations to account for diverging patterns of action in warfare, politics, and diplomacy. He shows how Western and Chinese strategies work in several domains (the battlefield, for example) and analyzes two resulting acts of war. The Chinese strategist manipulates his own troops and the enemy to win a battle without waging war and to bring about victory effortlessly. (...) Efficacity in China is thus conceived of in terms of transformation (as opposed to action) and manipulation, making it closer to what is understood as efficacy in the West. Jullien’s brilliant interpretations of an array of recondite texts are key to understanding our own conceptions of action, time, and reality in this foray into the world of Chinese thought. In its clear and penetrating characterization of two contrasting views of reality from a heretofore unexplored perspective, A Treatise on Efficacy will be of central importance in the intellectual debate between East and West. (shrink)

This enlarged edition of Mario Bunge's Dictionary of Philosophy is a superb reference work for both students and professional philosophers.

La philosophie bergsonnienne a rendu le monde de ses contemporains moins opaque, les aidant à lui trouver un sens. Si la France cartésienne coïncide avec les partisans de la démocratie parlementaire ancrée à gauche, celle de Bergson recrute ses plus gros bataillons dans la droite nationale, conservatrice, mais également dans une gauche antiparlementaire, révolutionnaire.

Shortly after his death in 1997, the New York Review of Books called him “one of the most influential men in contemporary France.” Lies, Passions, and Illusions is a fitting capstone to this celebrated author’s oeuvre: a late-career ...

"Lettre à l'Autre. Comment empêcher que la présence, en s'instaurant, s'installe? Qu'elle s'enlise de ce qu'elle se réalise et s'abîme dans la durée? Les Amants en sont menacés..."--Page 4 of cover.

If we accept the idea that the value of a “logic” depends on its ability to fit the usual meaning of the “logical constants” which it formalises and the inferences we draw on their basis, we may ask if the meaning of “possible” is well captured by normal modal logic. We are faced with the following puzzle: if is meaningful and non contradictory is it not a logical truth that ? First, it is shown why there is no logical law (...) of the form , being a neutral wff, and then some philosophical conclusions are drawn: “possible” relative to truth must be distinguished from possible “relative” to meaning, and the former only is formalised in modal logic. (shrink)

We propose a new approach to the study of introspection. Instead of asking what form introspection actually takes in humans or other animals, we ask what forms it could take, in natural or artificial minds. What are the dimensions along which forms of introspection could vary? This is a relatively unexplored question, but it is one that has the potential to open new avenues of study and reveal new connections between existing ones. It may, for example, focus attention on possible (...) forms of introspection radically different from the human one and help to integrate competing theories of human introspection in a non-adversarial manner. We introduce and motivate the project, provide a preliminary mapping of the space of possible forms of introspection, and sketch a programme for interdisciplinary research on the topic. (shrink)

This book is a close reading of Jacques Lacan’s seminal essay, “The Agency of the Letter in the Unconscious or Reason Since Freud, ” selected for the particular light it casts on Lacan’s complex relation to linguistics, psychoanalysis, and philosophy. It clarifies the way Lacan renews or transforms the psychoanalytic field, through his diversion of Saussure’s theory of the sign, his radicalization of Freud’s fundamental concepts, and his subversion of dominant philosophical values. The authors argue, however, that Lacan’s discourse is (...) marked by a deep ambiguity: while he invents a new “language,” he nonetheless maintains the traditional metaphysical motifs of systemacity, foundation, and truth. (shrink)

Thinking involves many elements of sound that philosophical tradition has repressed. Breathing, rhythms and collateral noises participate in the making of idealities, even the most abstract. In order to hear them, the voice needs to be considered as one sound among others and as multiple, even when it comes from the same speaker, following different protocols of enunciation. Listening to the recordings of seminars and studying the role played by modern sound technologies make it possible to hear subterranean meanings and (...) tensions at the heart of mental elaboration. Thinkers and writers could be defined by the way they handle the acoustic environments favourable to the way they speak and write, whether by selection, mixing or silence. An ‘acousmatic’ reading aims to listen to this sonic investment in texts and to hear the complex vibrations of their thought. (shrink)

Nanotechnology is an important platform technology which will add new features like improved biocompatibility, smaller size, and more sophisticated electronics to neuro-implants improving their therapeutic potential. Especially in view of possible advantages for patients, research and development of nanotechnologically improved neuro implants is a moral obligation. However, the development of brain implants by itself touches many ethical, social and legal issues, which also apply in a specific way to devices enabled or improved by nanotechnology. For researchers developing nanotechnology such issues (...) are rather distant from their daily work in the lab, but as soon as they use their materials or devices in medical applications such as therapy of brain diseases they have to be aware of and deal with them. This paper is intended to raise sensitivity for the ethical, legal and social aspects (ELSA) involved in applying nanotechnology in brain implants or other devices by highlighting the short term problems of testing and clinical trials within the existing regulatory frameworks (A), the short and medium-term questions of risks in the application of the devices (B) and the long-term perspectives related to problems of enhancement (C). To identify and address such issues properly nanotechnologists should involve ethical, legal and social experts and regulatory bodies in their research as early as possible. This will help to remove pressure from regulatory bodies, to settle public concern and to prevent non-acceptable developments for the benefit of the patients. (shrink)

IntroductionClassifying the ethical issues in clinical ethics consultations is important to clinical practice and scholarship. We conducted a systematic review to characterize the typologies used to analyze clinical ethics consultations.MethodsWe identified empirical studies of clinical ethics consultation that reported types of ethical issues using PubMed. We screened these articles based on their titles and abstracts, and then by a review of their full text. We extracted study characteristics and typologies and coded the typologies.ResultsWe reviewed 428 articles; 30 of the articles (...) fulfilled our inclusion criteria. We identified 27 unique typologies. Each typology contained five to 47 categories (mean = 18). The most common categories were do-not-attempt-resuscitation orders (19 typologies, 70 percent), capacity (18 typologies, 67 percent), withholding (18 typologies, 67 percent), withdrawing (17 typologies, 63 percent), and surrogate or proxy (16 typologies, 59 percent). Only seven (26 percent) of the typologies contained all five of the most common categories. The typologies we used to characterize clinical ethics consultations exhibit significant heterogeneity and several conceptual limitations. A common typology is needed whose development may require multi-institutional collaboration and could be facilitated by professional organizations. (shrink)

Théorie économique élaborée dans les années 1960, l'hypothèse d'instabilité financière postule que le système capitaliste est instable par essence : toute phase d'équilibre apparent ne fait qu'encourager les acteurs du marché à prendre davantage de risques, qui provoquent de nouvelles crises. Décriée à l'époque, cette analyse est aujourd'hui considérée comme l'une des plus à même d'expliquer la crise actuelle. Elle offre une première approche passionnante d’une oeuvre dense, jusqu’à présent méconnue en France.

A defence of the 'pragmatic' theory of anaphora (which stresses the analogy between anaphora and deixis) against an argument put forward by Gareth Evans.

A brief synoptic parallel -- Taking the side of the 'modern' in philosophy -- Old and new relations between science and philosophy -- Matrices and principles -- Subtraction and superposition -- Philosophy and mathematics in the mirror -- Ontology and materiality -- Philo-fiction.